Canada price comparison · Florida
Xifaxan from Canada vs. U.S. price (2026)
Last updated October 9, 2026 · Reviewed by the LowerScript editorial team · Español
Short answer. Xifaxan (rifaximin) was listed at $764.01 for 60 tabs (550mg, Product of Canada) at Great North Pharmacy on October 9, 2026. The seller lists it as Zaxine. Near Tampa (ZIP 33602), the lowest LowerScript price we found was $6,409.64 for brand-name Xifaxan (550 mg, qty 90, as of October 9, 2026). From October 22, 2026, U.S. Customs suspends the low-value “de minimis” shipping exemption, and Canadian mail-order pharmacies expect prescription shipments to Americans to stop or become much harder.
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Xifaxan: Canadian price vs. Tampa price
| Medicine | Canadian online pharmacy (listed price, source) | LowerScript near Tampa: brand-name | LowerScript near Tampa: generic |
|---|---|---|---|
| Xifaxan (rifaximin) IBS with diarrhea, liver sold in Canada as Zaxine Compare your price at LowerScript | $764.01 for 60 tabs 550mg · ≈ $1,146.02 per 30 days · brand-name listing Product of Canada · Great North Pharmacy | $6,409.64 550 mg · qty 90 · as of Oct 9 | — |
Canadian price: Great North Pharmacy’s public product page, captured October 9, 2026. The page shows prices with a “$” and does not name the currency; we treat them as U.S. dollars (see the method note on the Florida Canada guide). Shipping is not included. LowerScript prices come from our price tool at ZIP 33602 (Tampa): the lowest price among nearby in-network pharmacies for the strength and quantity shown. Prices change, and strengths and packs can differ between countries, so compare the labels. This page compares listed prices; it is not a recommendation to buy from any seller and not medical advice.
What changes on October 22
The Associated Press reported on October 8, 2026 that the “de minimis” exemption for shipments valued under $800 is suspended starting October 22, 2026, and that medications mailed from outside the U.S. will then need additional data and a bond. The rule does not specifically target Canadian drugs, and this page takes no position on it. Source: Associated Press, via U.S. News, October 8, 2026.
Is there a generic?
Our data does not list a U.S. generic for Xifaxan, so we show no generic price. Compare your price at LowerScript.
Frequently asked questions
How much is Xifaxan in Canada compared with Tampa?
Xifaxan (rifaximin) was listed at $764.01 for 60 tabs (550mg, Product of Canada) at Great North Pharmacy on October 9, 2026. The seller lists it as Zaxine. Near Tampa (ZIP 33602), the lowest LowerScript price we found was $6,409.64 for brand-name Xifaxan (550 mg, qty 90, as of October 9, 2026). Shipping is not included in the Canadian price and prices change, so check the current price of your own medicine and strength.
Will my Xifaxan order from Canada still arrive after October 22?
We can’t predict that. The Associated Press reports that Canadian pharmacies expect shipments to Americans to stop or become much harder once the federal rule takes effect on October 22. Compare your price at LowerScript before your next refill.
Is LowerScript insurance?
No. LowerScript is a free prescription discount program, not insurance. At a participating pharmacy you pay the discounted cash price instead of using insurance for that fill.
Is there a generic of Xifaxan?
Our data does not list a U.S. generic for Xifaxan, so we show no generic price. Compare your price at LowerScript.
This guide is general information, not medical, legal or financial advice. LowerScript is a prescription discount program, not insurance.