Mental health · North Carolina prescription prices
Sertraline (Zoloft) prices in North Carolina
Last updated September 4, 2026 · Reviewed by the LowerScript editorial team · Español
Sertraline is a selective serotonin reuptake inhibitor (SSRI) used to treat depression, anxiety, OCD, panic disorder and PTSD. In North Carolina there is no fixed retail price for sertraline — the cash price varies by pharmacy and dose. With the free LowerScript discount card you can compare prices at nearby pharmacies and save up to 80% off the cash price, with no insurance, sign-up or fees. Check today's sertraline price to see the current cost near you.
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Quick facts
| Medication | Sertraline |
|---|---|
| Brand name | Zoloft |
| Generic name | Sertraline |
| Drug class | selective serotonin reuptake inhibitor (SSRI) |
| Common uses | Treat depression, anxiety, OCD, panic disorder and PTSD |
| Prescription required | Yes |
| Available as generic | Yes |
| Insurance required | No |
| LowerScript accepted | Yes |
What does sertraline cost in North Carolina?
Generic sertraline is affordable, but cash prices still vary between pharmacies. Retail prices vary by pharmacy, and insurance is not always the cheapest option — sometimes the discounted cash price is lower than a copay. Prices also change often, so the most reliable number is a live one. Check today's sertraline price to see the current cost near you.
How LowerScript helps
LowerScript lets you compare sertraline prices across nearby North Carolina pharmacies and pay the lower cash amount. The card is free — no membership, no insurance and no sign-up. Just show it at the pharmacy counter.
Potential savings
North Carolina residents can save up to 80% off the cash price of eligible prescriptions. The biggest savings tend to show up where pharmacy prices differ the most, so comparing before you fill is worth it for sertraline.
Where to use LowerScript
Your free card works for sertraline at most North Carolina pharmacies, including:
- CVS
- Walgreens
- Publix
- Food Lion
- Walmart
- Costco
How sertraline works
Sertraline is a selective serotonin reuptake inhibitor (SSRI) used to treat depression, anxiety, OCD, panic disorder and PTSD.
Common dosages
25, 50 and 100 mg tablets, once daily.
Frequently asked questions
What is sertraline?
Sertraline is a selective serotonin reuptake inhibitor (SSRI) used to treat depression, anxiety, OCD, panic disorder and PTSD.
Is generic Zoloft cheaper?
Yes — generic sertraline costs far less than brand Zoloft and is widely stocked.
How much can I save on sertraline in North Carolina?
North Carolina residents can save up to 80% off the cash price of eligible prescriptions, depending on the medication, dose and pharmacy. Because sertraline prices vary between pharmacies, comparing first is the best way to find the lowest cost.
Can I use LowerScript for sertraline with Medicare?
You can't combine LowerScript with Medicare on the same purchase, but you can choose the lower price — pay the sertraline cash price when it beats your plan copay. Ask the pharmacist to compare both.
Can I use LowerScript with insurance?
LowerScript isn't insurance and can't be combined with it on the same claim, but you can use whichever is cheaper. When the sertraline cash price is below your copay, use LowerScript instead.
Where can I use the LowerScript card for sertraline?
At most North Carolina pharmacies, including CVS, Walgreens, Walmart, Harris Teeter, Publix, Food Lion and many independents. Show the card at the counter and ask the pharmacist to process it using the RxBIN, RxPCN and RxGRP.
Is the LowerScript card free?
Yes. LowerScript is completely free — no membership, no sign-up and no fees. Show the card at the pharmacy to get the discount.
This page is general information, not medical advice. Never start, stop or change a medication without talking to your prescriber. LowerScript is a discount program, not insurance.
Reference information: prescribing details, approved uses and dosage for sertraline are published in the FDA drug labeling on DailyMed (NIH). Savings-network facts: SingleCare. Reference links checked July 2026.
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